Deoxyribonucleic acid DNA) is a molecule composed of two chains that
coil around each other to form a double helix carrying genetic instructions for
the development, functioning, growth and reproduction of all known organisms
and many viruses. DNA and ribonucleic acid (RNA) are nucleic acids; alongside
proteins, lipids and complex carbohydrates (polysaccharides), nucleic acids are
one of the four major types of macromolecules that are essential for all known
forms of life.
The two DNA strands are also known as polynucleotides as
they are composed of simpler monomeric units called nucleotides. Each
nucleotide is composed of one of four nitrogen-containing nucleobases (cytosine
[C], guanine [G], adenine [A] or thymine [T]), a sugar called deoxyribose, and
a phosphate group. The nucleotides are joined to one another in a chain by
covalent bonds between the sugar of one nucleotide and the phosphate of the
next, resulting in an alternating sugar-phosphate backbone. The nitrogenous
bases of the two separate polynucleotide strands are bound together, according
to base pairing rules (A with T and C with G), with hydrogen bonds to make
double-stranded DNA. The complementary nitrogenous bases are divided into two
groups, pyrimidines and purines. In DNA, the pyrimidines are thymine and
cytosine; the purines are adenine and guanine.
Reference DNA
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