Antipyretics

Antipyretics are substances that reduce fever.

Antipyretics cause the hypothalamus to override a prostaglandin-induced increase in temperature. The body then works to lower the temperature, which results in a reduction in fever.

 Ibuprofen and aspirin, which are non-steroidal anti-inflammatory drugs (NSAIDs) used primarily as analgesics , and antipyretic .

Example:

1.Paracetamol (C8H9NO2)

It is also known as acetaminophen and APAP, is a medication used to treat pain and fever. It is typically used for mild to moderate pain relief.

It  is also used for severe pain, such as cancer pain and pain after surgery.

It is typically used either by mouth or rectally, but is also available by injection into a vein.Effects last between 2 to 4 hours.

It is generally safe at recommended doses.

The recommended maximum daily dose for an adult is 3 or 4 grams.

 Higher doses may lead to toxicity, including liver failure, serious skin rashes may rarely occur.

It appears to be safe during pregnancy and when breastfeeding.

 In those with liver disease, it may still be used, but in lower doses. It is classified as a mild analgesic.

It does not have significant anti-inflammatory activity.

 

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Medicinal uses:

It  is used for reducing fever in people of all ages.

It is  used to treat fever in children only if their temperature is higher than 38.5 °C

It  is used for the relief of mild to moderate pain.

It is used  for people with arthritis pain of the hip, hand and dental pain.

Adverse Effect:

Liver damages, asthma, diarrhea, vomiting and abdominal pain.

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Source: Wikipedia